Multimodal Metabolic Analysis of Tumors and Therapeutic Responses

Dr. Reznik and Dr. Hakimi will integrate two distinct data modalities, metabolomics, and transcriptomics, in order to study metabolic adaptations across cancer. Specifically, they will develop integrative analytical approaches to study the metabolic features defining distinct immune-hot/immune-cold microenvironments, and develop transcriptome-based signatures for the in silico inference of metabolite levels.